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Date: June 2025, Version 4

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It is important to correctly treat an infection. Quinolone antibiotics can be used in pregnancy if recommended by your doctor.

What are they?

The quinolones are a group of antibiotics that include ciprofloxacin (Ciproxin)®, levofloxacin (Quinsair®), moxifloxacin (Moxivig®), and ofloxacin (Exocin®). Quinolones are used to treat a wide range of infections.

Benefits

What are the benefits of using a quinolone antibiotic in pregnancy?

Quinolones can treat many types of infection and prevent serious complications to both you and your baby.

Risks

What are the risks of using a quinolone antibiotic in pregnancy?

There is no good evidence that use of a quinolone antibiotic in pregnancy will harm your baby.

Quinolone antibiotics can cause serious side effects such as damage to joints and muscles, as well as effects on the nerves and mood changes. For this reason, they are usually only prescribed if there is no alternative treatment for a serious infection.

Alternatives

Are there any alternatives to taking a quinolone antibiotic in pregnancy?

Yes, a different antibiotic will usually be tried first. If a quinolone antibiotic is recommended, a doctor will be able to discuss why it is the best treatment.

No treatment

What if I prefer not to take medicines in pregnancy?

It is important that an infection in pregnancy is well-treated as it can lead to very unpleasant symptoms, as well as serious complications for both mother and baby.

A doctor will only prescribe medicines when necessary and will be happy to talk about any concerns.

Will I or my baby need extra monitoring?

As part of routine antenatal care, most women will be offered a very detailed scan at around 20 weeks of pregnancy to check the baby’s development. No extra monitoring for major birth defects is required following use of a quinolone antibiotic.

Are there any risks to my baby if the father has taken a quinolone antibiotic?

There is no evidence that quinolone antibiotics used by the father can harm the baby through effects on the sperm.

Who can I talk to if I have questions?

If you have any questions about the information in this leaflet, please discuss them with your health care provider. They can access more detailed medical and scientific information from www.uktis.org.

How can I help to improve drug safety information for pregnant women in the future?

Our online reporting system (MyBump Portal) allows women who are currently pregnant to create a secure record of their pregnancy, collected through a series of questionnaires. You will be asked to enter information about your health, whether or not you take any medicines, your pregnancy outcome and your child's development. You can update your details at any time during pregnancy or afterwards. This information will help us better understand how medicines affect the health of pregnant women and their babies. Please visit the MyBump Portal to register.

General information
Sadly, miscarriage and birth defects can occur in any pregnancy.

Miscarriage occurs in about 1 in every 5 pregnancies, and 1 in every 40 babies are born with a birth defect. This is called the ‘background risk’ and happens whether medication is taken or not.

Most medicines cross the placenta and reach the baby. For many medications this is not a problem. However, some medicines can affect a baby’s growth and development.

If you take regular medication and are planning to conceive, you should discuss whether your medicine is safe to continue with your doctor/health care team before becoming pregnant. If you have an unplanned pregnancy while taking a medicine, you should tell your doctor as soon as possible.

If a new medicine is suggested for you during pregnancy, please make sure that the person prescribing it knows that you are pregnant. If you have any concerns about a medicine, you can check with your doctor, midwife or pharmacist.

Our Bumps information leaflets provide information about the effects of medicines in pregnancy so that you can decide, together with your healthcare provider, what is best for you and your baby.