Baclofen
Quick read
Baclofen use may occasionally be advised in pregnancy if it is needed to control severe muscle spasms.
What is it?
Baclofen (Lyflex®, Lioresal®) is a medicine used to treat severe muscle tightness and muscle spasms caused by an underlying brain condition. Baclofen can be given by mouth or intrathecally (into the fluid-filled space around the spinal cord).
Benefits
What are the benefits of taking baclofen in pregnancy?
Baclofen use may be advised to control pain and improve problems with mobility and day-to-day function that are caused by severe muscle spasms. In these cases, the benefits to both woman and baby of ensuring the woman remains well are likely to outweigh any possible risks.
Risks
Are there any risks of taking baclofen during pregnancy?
Baclofen use in pregnancy has been studied in only around 150 women. Although the available information does not suggest it harms the baby in the womb, much more information needs to be collected to confirm this.
Baclofen given intrathecally is thought to reach the baby in very small amounts that are unlikely to cause harm.
Baclofen taken by mouth can potentially cause short-term withdrawal symptoms in the newborn baby if taken in the weeks before delivery. For this reason, a baby may be monitored for some time after birth to check for symptoms such as jitteriness, difficulty sleeping and breathing problems.
Alternatives
Are there any alternatives to taking baclofen?
Possibly. There may be other medications that can be used depending on the specific circumstances. When a particular medicine is being offered, a doctor will be able to explain why it is the best choice.
No treatment
What if I prefer not to take baclofen during pregnancy?
Reduced mobility and chronic pain can greatly affect quality of life. Baclofen will only be offered in pregnancy if the benefits of use outweigh the possible risks. A doctor or specialist will be happy to discuss this.
Will my baby need extra monitoring?
In the UK, all women will be offered a very detailed scan at around 20 weeks of pregnancy as part of their routine antenatal care. No additional monitoring of the baby is required due to use of baclofen. However, closer monitoring may be offered to women with some of the underlying health conditions that baclofen is used to treat.
Are there any risks to my baby if the father takes baclofen?
We would not expect any increased risk to the baby if the father took baclofen around the time of conception.
Who can I talk to if I have questions?
If you have any questions about the information in this leaflet, please discuss them with your health care provider. They can access more detailed medical and scientific information from www.uktis.org.